A HIGHER CALLING: HOW ISRAELI MARIJUANA RESEARCH CHANGED THE WORLD
“The problem is that for many years, marijuana was put on the [same] scale as cocaine and morphine.”
BY AVI JORISCH
JUNE 19, 2018 21:58
As much of the world debates how to address marijuana use, the vast majority of American states have legalized it or allow it for medical purposes. Global pharmaceutical companies and hospitals seeking effective treatments using cannabis should look to Professor Raphael Mechoulam, a scientist at Hebrew University. Mechoulam, a pioneer in the field, was the first to isolate, analyze and synthesize the major psychoactive and non-psychoactive compounds in cannabis and has developed a number of revolutionary marijuana-related treatments.
Today, roughly 147 million people use medical marijuana for effective relief of various ailments, including AIDS, multiple sclerosis, Crohn’s disease, cancer treatment side effects and Parkinson’s. Experts believe these numbers will grow exponentially in the coming years, and Mechoulam is now widely recognized as the godfather of medical marijuana, the high priest of his field.
Oklahomans Shawn Jenkins & Ray Jennings addressed a packed hall at the Oklahoma State legislature on Wednesday, July 25th. Jenkins told of his son's severe health needs and how cannabis medicines have greatly improved his health, development, and quality of life.
Ray Jennings told of his fight with stage 4 cancer and how his family convinced him to try cannabis medicines when he was near death.
The State Health Dept. soon after appointed Jennings to the Food Safety & Packaging board for the Medical Marijuana Authority. Jennings goes into further details in this home video.
Cathy Jordan of Florida – Lou Gehrig’s Disease (ALS )
I used to be a hairdresser from New Castle, DE, but now I’m a medical marijuana patient & activist, living near Tampa, FL.
I was diagnosed with Amyotrophic Lateral Sclerosis (ALS or “Lou Gehrig’s Disease”) in 1986 (I was 36), was told by my doctor not to smoke anything, standard advice for a new ALS patient, suffered typical deterioration of my body over the next two years and prepared for my death – ALS is a terminal illness and I probably had only another year or two.
Then, in 1989, standing on a beach in Sarasota, FL, I was passed a “joint” and said “Why not?” After just a few puffs, I had a wonderful feeling – that my disease had stopped! I’ve been smoking ever since – for twenty-one years now, and I think I’m aging quite well, thank you.
Cannabis (the scientific name for marijuana) works for me by drying up my saliva (ALS patients often drown in their own fluids), helping me cough and stimulating my lungs through its bronchodilation action.
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Brenda L. of Ohio: Breast Cancer
“Eight years ago, Brenda was diagnosed with breast cancer. It was in stage I when they found it. She underwent the lumpectomy and sentinel node biopsy.
A lumpectomy is where just the tumor is removed as well as the normal breast tissue that closely surrounds the tumor. Sentinel node refers to the first lymph node(s) that drains from the breast tumor area (found by injecting a radioactive dye).
“They shoot radiation into your breast and they follow it up to the nodes to make sure that you don’t have cancer in your lymph nodes. And I did not, so all I had to have was radiation…and hormone therapy. Because my cancer was fed by the estrogen.”
Tamoxifen is used to treat certain types of breast cancer that require estrogen to grow. It’s often used following surgery and radiation. (Drugs.com can provide more information on this line of treatment.)
Barbara Leigh is a young mother to a little girl who has faced devastating seizures every hour of her life.
It's been ten days since Barbara started her daughter, Nova Leigh, on THC cannabis oil. Ten days without a seizure. When one did come, another dose of the oil and it stopped almost immediately.
Barbara's daughter, Nova Leigh, suffers from a rare birth defect called Shizencehaly. She was also born without a thyroid and only 25% of her brain developed.
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Everyone told Barbara that cannabis could not possibly help Nova, but it did. Here is Barbara's account of the ten days following cannabis oil therapy.
Heath Poland suffers from ADHD (Attention Deficit Disorder) and Bipolar Disorder. Like so many who suffer from mental illness, he spent much of his life mis-diagnosed and improperly and/or over-medicated. Medicating with cannabis calms the symptoms of his disorders and makes the side effects from the pharmaceuticals more tolerable.
Beth Wilkinson of Kansas: Epilepsy
Beth is originally from Cedar Rapids, Iowa. That’s where she grew up. She got her degree from the University of Northern Iowa. She has a degree in Art Education.
Currently Beth lives in Lawrence, Kansas. It’s turned out to be a really nice place for her and her family to live.
In 1986, Beth was riding horses with a friend. Her horse fell on her and she suffered a TBI, (traumatic brain injury), which landed her in a coma for over a week.
When she came out of the coma, she had to learn everything all over again. Her son was two years old then. “ …so, we basically grew up together.”
She didn’t have any further complications from her injury for years. She finished up her degree and she later moved to Minnesota. But it was there that she began experiencing seizures and black outs.
So she had to start seeing a Neurologist. She was put on Dilantin and stayed on it for years.
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Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.
Cannabinoid receptors are of a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and phytocannabinoids (plant based cannabinoids) are lipophilic, such as fat soluble compounds.
There are currently two known subtypes of cannabinoid receptors, termed CB1 and CB2. The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. Mounting evidence suggests that there are novel cannabinoid receptors that is, non-CB1 and non-CB2, which are expressed in endothelial cells and in the CNS. In 2007, the binding of several cannabinoids to the G protein-coupled receptor GPR55 in the brain was described.
Read More.. Heather DeMian of Columbia, Missouri: Ehlers-Danlos Syndromea
Heather is thirty-six years old and confined to a wheelchair. Heather was born with a rare genetic condition called Vascular Type Ehlers-Danlos Syndrome.
It’s a defect in her type three collagen that weakens the walls of her blood vessels, organs, and esophagus. “Everything is very weak.”
It makes her joints dislocate very easily. “When you see a new doctor and they see that you have Ehlers-Danlos, they immediately ask ‘what tricks can you do?’ ” A cynical smile comes over Heather’s face.
But condition is no laughing matter. It causes her a lot of pain and gastrointestinal problems, which are further aggravated by the pain meds that are prescribed to her.
Heather takes Zofran, an anti-nausea medication. “Zofran suppresses the gag reflex maybe half the time.” Her Medicaid pays roughly $1200 per month for her to have this drug.
She also takes Marinol, a pharmaceutical synthetic of the cannabinoid THC that is found in cannabis. Heather’s Marinol costs Medicaid roughly $1500 per month.
Together, these prescriptions total $2700 per month or $32400 per year, just to try to suppress Heather’s urge to vomit. Unfortunately, they rarely do. She has to carry a plastic container everywhere she goes for when the urge to vomit comes upon her. Obviously, she doesn’t get to go out very much.
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